Deep brain stimulation

From HCE Wiki - The Human Cognitive Enhancement Wiki
Revision as of 11:06, 13 April 2017 by Zuzana Rybaříková (talk | contribs) (Main characteristics)
Jump to navigation Jump to search

List of Deep brain stimulation devices:

https://tribune.com.pk/story/1337579/scientists-test-deep-brain-stimulation-potential-anorexia-therapy/

http://www.sciencedirect.com/science/article/pii/S1353802015004174


Deep brain stimulation (DBS) is a neurosurgical technique in which electrodes are implanted into patient's brain. Although, patients have to undergo an invasive surgery, it is growing field of neurosurgery.[1] DBS proved to be cost-effective in a treatment of certain severe neurological diseases as Parkinson's disease, essential tremor, dystonia, OCD or epilepsy.[2] The treatment of other neurological and psychiatric diseases as depression or chronic pain is examined intensively.[1]

DBS is not a cure. None of the diseases to which is used are curable at the moment. It could however, eliminate symptoms of the diseases, which negatively affected the lives of the patients.[3] DBS is used in medical devices, which are on prescription, the use for cognitive enhancement is highly limited. However, certain cases of possible cognitive enhancement were also reported.[4]

[5]

Main Characteristics

Deep brain stimulation consist in stimulation of a brain by the electrodes, which are implanted in the brain. The electrodes are often referred as leads and are linked with pulse generator via wires. The different diseases could be treated with one device, since the output of the treatment is dependant on the position of electrodes.[6] The pulse generator could be rechargeable or non-rechargeable[7] and could be implanted in the chest[8] or under the scalp[9].

The surgery usually consists of two procedures. Firstly, the electrodes are implanted into patient's brain. The patient has to be awake during the surgery in order to surgeons could see the impact of the stimulation.[10] There are several electronic devices, which could help surgeons to reach the correct spot in the brain.[11]

Since DBS does not require a destruction of any area in the brain, it is reversible procedure.[12]

The ways of stimulation

Historical overview

Purpose

Important Dates

  • about 5000 B.C. the first trephinations were conducted in South America.[2]
  • 1960s - the first attempts of deep brain stimulation were conducted,[2] they were abandoned due to high mortality rate[12]
  • 1987 - the research on deep brain stimulation of the thalamic nucleus ventralis intermedius to treat symptoms of Parkinson's disease was published[13]
  • 1993 - deep brain stimulation of subthalamic nucleus was introduced as a treatment of Parkinson's disease.[14]
  • 1997 - deep brain stimulation was approved as a treatment of Parkinson's disease by FDA.[8]

Enhancement/Therapy/Treatment

http://ve5kj6kj8s.scholar.serialssolutions.com/?sid=google&auinit=C&aulast=Andrews&atitle=Which+patients+with+dystonia+benefit+from+deep+brain+stimulation%3F+A+metaregression+of+individual+patient+outcomes&id=pmid:20841370

http://ve5kj6kj8s.scholar.serialssolutions.com/?sid=google&auinit=M&aulast=Tagliati&atitle=Long%E2%80%90Term+management+of+DBS+in+dystonia:+Response+to+stimulation,+adverse+events,+battery+changes,+and+special+considerations&id=doi:10.1002/mds.23535&title=Movement+disorders&volume=26&issue=S1&date=2011&spage=S54&issn=0885-3185

http://ve5kj6kj8s.scholar.serialssolutions.com/?sid=google&auinit=C&aulast=Fukaya&atitle=Deep+brain+stimulation+for+Parkinson%E2%80%99s+disease:+recent+trends+and+future+direction&id=doi:10.2176/nmc.ra.2014-0446&title=Neurologia+medico-chirurgica&volume=55&issue=5&date=2015&spage=422&issn=0470-8105

http://ve5kj6kj8s.scholar.serialssolutions.com/?sid=google&auinit=JF&aulast=Baizabal-Carvallo&atitle=The+safety+and+efficacy+of+thalamic+deep+brain+stimulation+in+essential+tremor:+10+years+and+beyond&id=pmid:24096713

pain - http://www.eurekalert.org/pub_releases/2016-04/uota-eso040416.php

Anorexia nervosa - http://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(17)30076-7/fulltext

Bipolar - http://neurocritic.blogspot.cz/2012/01/deep-brain-stimulation-for-bipolar.html

Alzheimer's disease - http://link.springer.com/article/10.1007/s10072-015-2120-6

Ethical & Health Issues

Discrepancy in the DBS programme - https://defeatparkinsons.com/2015/11/06/taking-a-closer-look-at-dbs-by-dr-de-leon/

Public & Media Impact and Presentation

https://www.youtube.com/watch?v=7wYfafhuITA

http://www.espn.com/espn/story/_/id/8194683/davis-taylor-phinney

https://www.youtube.com/watch?v=aHxd_IIbxE4

https://www.youtube.com/watch?v=fDz6R82h6qU

https://www.youtube.com/watch?v=L_c2yI5otTM

https://www.youtube.com/watch?v=Jk0TGTdCXgQ

https://www.youtube.com/watch?v=LON36XhpdDs

http://www.medgadget.com/2013/06/a-fantastic-demonstration-of-deep-brain-stimulation-for-parkinsons.html

Public Policy

Related Technologies, Projects or Scientific Research

References

  1. ↑ 1.0 1.1 GOSSET, Nathalie, DIETZ, Nicholas. IEEE Pulse [online]. Unlocking Pain: Deep brain stimulation might be the key to easing depression and chronic pain. 2015, Mar 15. Available online at: http://pulse.embs.org/march-2015/unlocking-pain/ (Retrieved 13th April, 2017).
  2. ↑ 2.0 2.1 2.2 LOZANO, Andres. Tuning the Brain. The Scientist [online]. 2013, Oct 28. Available online at: http://www.the-scientist.com/?articles.view/articleNo/38047/title/Tuning-the-Brain/ (Retrieved 12th April, 2017).
  3. ↑ U.S. Food and Drug Administration. FDA approves brain implant to help reduce Parkinson’s disease and essential tremor symptoms. U.S. Food and Drug Administration [online]. 2015, Jun 12. Available online at: https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm451152.htm (Retrieved 6th April, 2017).
  4. ↑ HAMANI, Clement. et al. Memory enhancement induced by hypothalamic/fornix deep brain stimulation. Annals of Neurology, 2008, 63(1), 119–123. Doi: 10.1002/ana.21295 Available online at: http://ve5kj6kj8s.scholar.serialssolutions.com/?sid=google&auinit=C&aulast=Hamani&atitle=Memory+enhancement+induced+by+hypothalamic/fornix+deep+brain+stimulation&id=doi:10.1002/ana.21295&title=Annals+of+neurology&volume=63&issue=1&date=2008&spage=119&issn=0364-5134 (Retrieved 13th April, 2017).
  5. ↑ DANCE, Amber. Deep-Brain Stimulation: An Electrode for All Occasions?. Alzforum [online]. 2010, May 25. Available online at: http://www.alzforum.org/news/research-news/deep-brain-stimulation-electrode-all-occasions (Retrieved 13th April, 2017).
  6. ↑ NORDQVIST, Joseph. What is Deep Brain Stimulation?. MedicalNewsToday [online]. 2016, Sep 7. Available online at: http://www.medicalnewstoday.com/articles/265445.php?utm_source=TrendMD&utm_medium=cpc&utm_campaign=Medical_News_Today_TrendMD_0 (Retrieved 11th April, 2017).
  7. ↑ GILLIES, Martin J. et al. Rechargeable vs. Nonrechargeable Internal Pulse Generators in the Management of Dystonia. Neuromodulation: Technology at the Neural Interface, 2013, 16(3), 226-229. Doi: 10.1111/ner.12026 Available online at: http://onlinelibrary.wiley.com/doi/10.1111/ner.12026/full (Retrieved 11th April, 2017).
  8. ↑ 8.0 8.1 DANCE, Amber. Deep-Brain Stimulation: Decade of Surgical Relief, Not Just for PD. Alzforum [online]. 2010, May 21. Available online at: http://www.alzforum.org/news/research-news/deep-brain-stimulation-theres-still-room-improvement (Retrieved 12th April, 2017).
  9. ↑ SIRVEN, J.I. Responsive Neurostimulation. Epilepsy Foundation [online]. 2014, May. Available online at: http://www.epilepsy.com/learn/treating-seizures-and-epilepsy/devices/responsive-neurostimulation (Retrieved 13th April, 2017).
  10. ↑ DANCE, Amber. Deep-Brain Stimulation: An Electrode for All Occasions?. Alzforum [online]. 2010, May 25. Available online at: http://www.alzforum.org/news/research-news/deep-brain-stimulation-electrode-all-occasions (Retrieved 13th April, 2017).
  11. ↑ DANCE, Amber. Deep-Brain Stimulation: There’s Still Room for Improvement. Alzforum [online]. 2010, May 25. Available online at: http://www.alzforum.org/news/research-news/deep-brain-stimulation-electrode-all-occasions (Retrieved 13th April, 2017).
  12. ↑ 12.0 12.1 BREIT, Sorin. Deep Brain Stimulation. Cell and Tissue Research, 2004, 318(1), 275–288. Doi: 10.1007/s00441-004-0936-0 Available online at: http://link.springer.com/article/10.1007/s00441-004-0936-0 (Retrieved 13th April, 2017).
  13. ↑ BENABID A.L. et al. Combined (Thalamotomy and Stimulation) Stereotactic Surgery of the VIM Thalamic Nucleus for Bilateral Parkinson Disease. Appl Neurophysiol, 1987, 50, 344–346 Doi: 10.1159/000100803 Available online at: https://www.karger.com/Article/Abstract/100803 (Retrieved 12th April, 2017).
  14. ↑ BENABID A.L. et al. Acute and long-term effects of subthalamic nucleus stimulation in Parkinson’s disease. Stereotact Funct Neurosurg, 1994, 62, 76–84. Doi: 10.1159/000098600 Available online at: https://www.karger.com/Article/Abstract/98600 (Retrieved 12th April, 2017).
Retrieved from "http://hcewiki.zcu.cz/hcewiki/index.php?title=Deep_brain_stimulation&oldid=6553"