3,183
edits
Changes
Jump to navigation
Jump to search
proof reading
For easier control, it is possible to download the Quell application for iOS<ref>Quell relief application available to download: https://itunes.apple.com/app/quell-relief/id972079954</ref> or Android<ref>Quell relief application available to download on GooglePlay: https://play.google.com/store/apps/details?id=com.neurometrix.quell</ref>. The company also offers [https://www.quellrelief.com/quell-user registration] of individual user's devices; this will allow company to collect measured data about user and treatment process and create a database (this registration is optional).
The mechanism of treatment lies in the following process: electrodes stimulate clusters of afferent sensory nerves, and this triggers the inhibition of pain in the brainstem. Inhibition comes up due to cascade neurotransmitter release. This descending process starts in the periaqueductal grey matter, continuing to the medulla and then into the spinal cord (its dorsal horn).<ref>Introducing Quell™, a 100% drug free technology proven to fight pain: https://www.quellrelief.com/files/Quell%20HCP%201%20page%20(3).pdf</ref> Body-produced opioids- enkephalins-cause inhibition of pain signal transmission while activating δ-opioid receptors. The described process is the core of the reason why this treatment is cleared as 100% drug-free. A more detailed description regarding TENS technology (not Quell in particular) is available in Johnson's book ''Transcutaneous Electrical Nerve Stimulation''.<ref name="johnson14" />
The company also claims, that Quell is twice as strong as previous TENS pain relieving products; thus, it does not have to be used locally, but only on the upper calf.<ref>NeuroMetrix Investor statement: http://investor.neurometrix.com/releasedetail.cfm?releaseid=923300, December 15, 2015</ref>
